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Abstract Achievement Award at the 67th American Society of Hematology (ASH) Meeting
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I am honoured to receive Abstract Achievement Award for my poster presented at the 67th Annual Meeting of the American Society of Hematology (ASH) in Orlando, Florida. Our work explored how aging influences alcohol-induced inflammation and promotes sustained upregulation of transposable elements in aged hematopoietic stem cells (HSCs). Notably, these changes are linked to a significant increased chromatin accesibility of retroelement–associated genomic loci enriched for several transcription factor binding sites such as CTCF, NFE2L2, FOXL1, and RUNX3 in aged HSCs, shedding light on how aging and alcohol together reshapes stem cell chromatin (epigenome) landscapes. The abstract is now published in Blood journal (DOI: https://doi.org/10.1182/blood-2025-1378)
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publications
Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo
Published in Nature Immunology, 2022
Long-term cultured AMs regain full identity after transfer.
Recommended citation: Subramanian, S., Busch, C.JL., Molawi, K. et al. "Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo." Nat Immunol 23. 458-468(2022).
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Isolation, Ex Vivo Expansion, and Lentiviral Transduction of Alveolar Macrophages. In: Mass, E. (eds) Tissue-Resident Macrophages
Published in Methods in Molecular Biology, 2023
Isolation, culture, and genetic modification of macrophages.
Recommended citation: Busch, C.JL., Subramanian, S., Linares, J., Favret, J., Yuda, R.A.A., Sieweke, M.H. "Isolation, Ex Vivo Expansion, and Lentiviral Transduction of Alveolar Macrophages. In: Mass, E. (eds) Tissue-Resident Macrophages." Methods in Molecular Biology, vol 2713. 231-251(2024).
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Combinatorial Effect of Chronic Alcohol Drinking and Age Perpetuates Myeloid-Biased Hematopoiesis Via Hematopoietic Stem Cell Senescence
Published in Blood, 2024
This paper is a published conference abstract at the 66th American Society of Hematology Symposium
Recommended citation: Yuda, Ridzky et al. (2024). "Combinatorial Effect of Chronic Alcohol Drinking and Age Perpetuates Myeloid-Biased Hematopoiesis Via Hematopoietic Stem Cell Senescence." Blood Volume 144 Supplement 1 . Page 2672.
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Chronic alcohol consumption epigenetically reactivates transposable elements in aged hematopoietic stem cells
Published in Blood, 2025
This paper is a published conference abstract that will be presented at the 67th American Society of Hematology Symposium
Recommended citation: Yuda, Ridzky et al. (2025). "Chronic alcohol consumption epigenetically reactivates transposable elements in aged hematopoietic stem cells." Blood 2025 vol 146 supplement 1 . Page 1378.
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Dietary serine restriction increases venetoclax efficacy in Acute Myeloid Leukemia
Published in Blood, 2025
This paper is a published conference abstract that was presented as poster at the 67th American Society of Hematology Symposium
Recommended citation: Malikarjun, Reddy et al. (2025). "Dietary serine restriction increases venetoclax efficacy in Acute Myeloid Leukemia." Blood 2025 vol 146 supplement 1 . Page 5046.
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Chronic alcohol consumption drives inflammaging and transposon derepression in hematopoietic stem and progenitor cells
Published in bioRxiv, Cold Spring Harbor Laboratory, 2025
Chronic alcohol, inflammaging, transposable elements, HSPCs
Recommended citation: Yuda, R.A.A., et al. "Chronic alcohol consumption drives inflammaging and transposon derepression in hematopoietic stem and progenitor cells." bioRxiv 2025..
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talks
Talk 1 on Relevant Topic in Your Field
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Conference Proceeding talk 3 on Relevant Topic in Your Field
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teaching
Teaching experience 1
Undergraduate course, University 1, Department, 2014
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Teaching experience 2
Workshop, University 1, Department, 2015
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